Rhythms of the Road: A Musical Motorhome Adventure from Chicago to New Orleans
If the open road calls to you with the hum of a bass guitar and the swing of a bluesy saxophone, there's no better journey than the one that follows the Blues Highway — US 61. This 15-day family RV road trip from Chicago to New Orleans isn't just a vacation. It’s a pilgrimage through the heartbeat of American music, culture, and soul.
With your campervan packed, your motorhome humming with excitement, and your playlist tuned to B.B. King, Aretha Franklin, Elvis, and Muddy Waters, it's time to start your road trip planning. The route planner is set — from the Windy City to the Big Easy, you're rolling through six states, iconic music landmarks, natural wonders, and a rhythm-infused slice of Americana.
From Chicago’s Blues Roots
Begin on South Lake Shore Drive, skimming the lakefront of Chicago. Before heading south, dive into the birthplace of modern blues at the Muddy Waters MOJO Museum, a lovingly preserved home-turned-shrine that echoes with guitar licks from the past.
Then take a short detour to The Forge Adventure Park & Ziplines, a family-friendly outdoor park that breaks up the musical immersion with fresh air and adrenaline — a good reminder that a great road trip includes balance.
Just outside the city, swing by Funks Grove Pure Maple Sirup Farm in Illinois for a sweet roadside stop. A jar of local maple syrup makes a great souvenir and RV pancake topping!
Gateway to the South
In Missouri, explore the Lewis and Clark Historic Site (Camp River Dubois), blending history and education for curious young travelers. Then cruise into St. Louis, where music takes center stage at the National Blues Museum. Nearby, BB's Jazz, Blues and Soups is the place for live tunes and soul food — kid-friendly in the early evening, with rich flavors and even richer harmonies.
Down into Tennessee – Country and Rock Collide
As your motorhome rolls south, Tennessee opens its musical vault. Paddle into nature with Cache Bayou Outfitters, offering a peaceful detour by kayak. Then step into legend at the Johnny Cash Museum and Elvis Presley's Recording Room in Nashville.
Don’t skip Honky Tonk Highway, where neon lights meet country chords. Even families will find daytime shows and boot-stomping fun. The Country Music Hall of Fame and Museum is both immersive and interactive — a great stop to help kids connect with America's music story.
In Chattanooga, the underground wonder of Ruby Falls and the aquatic delights of the Tennessee Aquarium are must-visits. These attractions are perfect breaks from long stretches of driving in your RV or campervan.
The Soul of Memphis
As you reach Memphis, things get legendary. Park your motorhome and spend time at Graceland, Sun Studio, and the Memphis Rock 'n' Soul Museum. Younger travelers will love the Elvis Presley Automobile Museum, where pink Cadillacs and shiny chrome dazzle like a living toy collection.
Don’t forget the Birthplace of Aretha Franklin, and groove into the evening at B.B. King’s Blues Club, where the spirit of the blues is alive and well.
Mississippi & Alabama: Hidden Gems
Just outside of the bigger cities, Howlin’ Wolf Blues Museum in Mississippi is a quieter tribute to a powerful voice of the Delta blues. At Dunn’s Falls Park, the roar of waterfalls offers a peaceful counterpoint to the constant rhythm of the road.
In Alabama, you'll feel a change in tempo — a slower drawl, more heat in the air, and nature beckoning. Keep your camera ready and your camper route planner set — this stretch rewards curiosity.
New Orleans: Where It All Comes Together
As the bayous begin to thicken and the Spanish moss hangs heavy, you know you're nearing New Orleans. Swap your wheels for a Honey Island Swamp Tour — a fun and educational wildlife excursion ideal for families.
Back in the city, take the New Orleans Music and Heritage Tour for a walking experience that dives deep into jazz and culture. At Mardi Gras World, kids and adults alike marvel at parade floats and costumes up close.
Finally, the New Orleans Jazz Museum and the famous Lakeside Shopping Center offer something for everyone before your RV journey ends.
Road Trip Planning Tips
How to plan a motorhome trip in the USA from Chicago to New Orleans camper route planner:
Use a trusted RV route planner like RV Trip Wizard or Campendium to map campsites and gas stations.
Some urban stops (like downtown Memphis or New Orleans) are best experienced by parking the RV outside the city and using local transit.
State parks along the route offer excellent, affordable campgrounds with hookups.
RV Travel Tip: Book campgrounds early in music-heavy cities like Nashville and Memphis — especially during festivals.
Best for Families: Mix music stops with outdoor adventures to keep kids engaged. Zipline parks, waterfalls, aquariums, and kayaking balance out the museum visits.